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Department of Physics

The Cavendish Laboratory


Born in Germany in 1973, Jochen Guck started his Physics training at the University of Würzburg, before he moved to the USA (MA and PhD in Physics from the University of Texas at Austin). He then led a research group at the University of Leipzig, Germany. Recently he accepted a Lecturer position at the Cambridge Physics Department. He is part of the Sector for Biological and Soft Systems and involved in the Physics of Medicine initiative.

Curriculum Vitae 


My research centers on exploring the global physical properties of biological cells and tissues and their importance for the cells' function and behavior. We also develop novel photonic tools for the study of their optical and mechanical properties. The ultimate goal is to gain further insight into biological systems and to utilize this insight for novel diagnostic and therapeutic medial approaches. 

Research Group - Biological and Soft SystemsPhysics of Medicine


Key publications: 

"Müller Cells are Living Optical Fibers in the Vertebrate Retina". K. Franze, J. Grosche, S. N. Skatchkov, S. Schinkinger, D. Schild, O. Uckermann, K. Travis, A. Reichenbach, and J. Guck. Proc. Natl. Acad. Sci. U.S.A. 104(20):8287-8292 (2007).

"High-Throughput Cell Analysis with a Microfluidic Optical Stretcher". B. Lincoln, S. Schinkinger, F. Wottawah, and J. Guck. Meth. Cell Biol. 83: 397-423 (2007).

"Viscoelastic properties of individual glial cells and neurons in the CNS". Y. Lu, K. Franze, G. Seifert, Ch. Steinhäuser, F. Kirchhoff, H. Wolburg, J. Guck, P. Janmey, E. Wei, J. Käs, and A. Reichenbach. Proc. Natl. Acad. Sci. U.S.A. 103(47):17759-177764 (2006)

"Optical Deformability as Inherent Cell Marker for Testing Malignant Transformation and Metastatic Competence". J. Guck, H. Erickson, R. Ananthakrishnan, D. Mitchell, M. Romeyke, S. Schinkinger, F. Wottawah, B. Lincoln, J. Käs, S. Ulvick, and C. Bilby. Biophys. J. 88(5):3689-3698 (2005).

"The Optical Stretcher: A Novel Laser Tool to Micromanipulate Cells". J. Guck, R. Ananthakrishnan, H. Mahmood, T.J. Moon, C.C. Cunningham, and J. Käs. Biophys. J. 81(2):767-784 (2001).

"Optical Deformability of Soft Biological Dielectrics". J. Guck, R. Ananthakrishnan, T.J. Moon, C.C. Cunningham, and J. Käs. Phys. Rev. Lett. 84(23):5451-5454 (2000)

My complete list of publications can be found here.

Principal Research Associate
Dr. Jochen  Guck

Contact Details

BSS Group
Cavendish Laboratory
JJ Thomson Avenue
+44 (0)1223 748914