Reader in Experimental Physics
Fellow of Gonville and Caius College
Room 916, Rutherford Building,
JJ Thomson Avenue
Cambridge CB3 0HE
After obtaining his PhD in low-temperature quantum transport from the Leibniz University of Hannover in Germany in 2002, Dr Keyser changed his research focus to single molecule biophysics by joining the Kavli Institute of Nanoscience at Delft University of Technology as a postdoctoral researcher. After demonstrating the first direct force measurements on DNA molecules in a nanopore, he joined Leipzig University with an Emmy Noether award as a group leader in 2006. Since 2007, Dr Keyser is a faculty member at the Cavendish laboratory working on the physics of membrane transport with financial support of an ERC consolidator grant (2010).
My main research is focused on understanding all transport processes through membranes of both biological and technological origin. Specifically, we are interested in the physics of ions, macromolecules and particles in confined geometries at the single molecule or particle level. We aim to exert maximum control over all parameters in the experiment using techniques such as: DNA (origami) self-assembly, optical trapping, particle tracking, fluorescence microscopy, electrophysiology, or micro-/nanofluidics. In parallel, we are always improving and developing new measurement techniques based on a combination of single molecule approaches.
N. Laohakunakorn, B. Gollnick, F. Moreno-Herreo, D. G. A. L. Aart, R. P. A Dullens, S. Ghosal, and U. F. Keyser. A Landau-Squire nanojet,. Nano Letters, 13(11):5141-5146, 2013.
S. Pagliara, C. Schwall, and U. F. Keyser. Optimizing Diffusive Transport Through a Synthetic Membrane Channel. Advanced Materials, 25(6):844-849, 2013.
N. A. W. Bell, C. R. Engst, M. Ablay, G. Divitini, C. Ducati, T. Liedl, and U. F. Keyser. DNA origami nanopores. Nano Letters (published online 20.12.2011), 12(1):512-517, 2012.
U. F. Keyser, S. Van Dorp, and S. G. Lemay. Tether forces in DNA electrophoresis. Chemical Society Reviews, 39:939 - 947, 2010.
S. van Dorp, U. F. Keyser, N. H. Dekker, C. Dekker, and S. G. Lemay. Origin of the electrophoretic force in nanopores. Nature Physics, 5:347, 2009.
Complete list of publications