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Dr. Sarah E Bohndiek

Dr. Sarah E Bohndiek

Reader in Biomedical Physics at the Cavendish Laboratory

Group Leader at the Cancer Research UK Cambridge Institute

Fellow of Corpus Christi College

Room 916, Rutherford Building
Cavendish Laboratory
JJ Thomson Avenue

Cambridge CB3 0HE
Office Phone: +44 (0)1223 337267

Biography:

Sarah Bohndiek completed her PhD in Radiation Physics at University College London in 2008 and then worked in both the UK (at Cambridge) and the USA (at Stanford) as a postdoctoral fellow in molecular imaging. Since 2013, Sarah has been a Group Leader at the University of Cambridge, where she is jointly appointed in the Department of Physics and the Cancer Research UK Cambridge Institute. 

Sarah’s team develop novel imaging approaches that can be applied to understand the role of the tumour microenvironment in cancer progression. They are also are active in translating their findings into clinical trials. Sarah was recently awarded the CRUK Future Leaders in Cancer Research Prize and SPIE Early Career Achievement Award in recognition of her interdisciplinary research innovation.

In addition to her research programme, Sarah also takes an active role in teaching and mentoring the next generation of scientists. She has acted as an ambassador for public engagement and interdisciplinary research training throughout her career and acknowledging her generosity in this regard, Sarah has received the MSCA Award for Nurturing Research Talent and been invited to deliver numerous talks on career development at both national and international workshops.

CV positions:

From 2017: Reader in Biomedical Physics, Department of Physics, Cambridge, U.K.

From 2014: Group Leader, Cancer Research UK Cambridge Institute, Cambridge, U.K.

From 2013: Fellow, Corpus Christi College, Cambridge, U.K.

2013 – 2017: University Lecturer in Biological / Biomedical Physics, Cavendish Laboratory, University of Cambridge, U.K.

2011 – 2013: Postdoctoral Scholar, Molecular Imaging Program at Stanford (MIPS), Stanford University, U.S.A. (Advisor: Prof. Sam Gambhir)

2009 – 2011: Junior Research Fellow (Non-stipendiary), Corpus Christi College, Cambridge, U.K.

2008 – 2011: Postdoctoral Research Fellow, Department of Biochemistry and Cancer Research UK Cambridge Research Institute, Cambridge, U.K. (Advisor: Prof. Kevin Brindle)

2005 – 2008: PhD Radiation Physics, Department of Medical Physics and Bioengineering, University College London (UCL), London, U.K. (Advisors: Prof. Robert Speller and Prof. Gary Royle)

Research Interests

We are a highly international and multidisciplinary research team whose passion is using new technological innovations to improve our understanding of metabolic (especially redox) processes in disease. We hope to use these innovations to improve cancer patient survival, by finding routes to enable earlier cancer detection and better prognostication. The cancer models we use range from single cells in petri dishes to intact living systems, including clinical trials in human patients. Our imaging techniques use excitation wavelengths that span the electromagnetic spectrum, with a current focus on the near-infrared, and we are particularly interested in nanophotonic detection methods.

Key Publications

Recent publications:

    D J Waterhouse, C R M Fitzpatrick, B W Pogue, J P B O’Connor and S E Bohndiek (2019) A roadmap for the clinical implementation of optical-imaging biomarkers. Nat Biomed Eng 3 339-353.

      J Yoon, J Joseph, D J Waterhouse, A S Luthman, G S D Gordon, M di Pietro, W Januszewicz, R C Fitzgerald and S E Bohndiek (2019) A clinically translatable hyperspectral endoscopy (HySE) system for imaging the gastrointestinal tract. Nat Comms 10 1902.

      Chosen as an ‘Editors’ Highlight’ by Dr Alfredo Sansone in ‘Stem Cells and Disease’

      M R Tomaszewski, M Gehrung, J Joseph, I Quiros-Gonzalez, J Disslehorst and S E Bohndiek (2018) Oxygen Enhanced- and Dynamic Contrast Enhanced- Optoacoustic Tomography provide surrogate biomarkers of tumour vascular function, hypoxia and necrosis. Cancer Res.78 (20) 5908-5991.

      B J Woodhams, L Bollepalli, H S Knowles, D M Kara, L Maggini, M de Volder, M Atature and S E Bohndiek (2018) Nanodiamond preparation and surface characterization for biological applications. Nanoscale 10 12169-12179

        Featured in the “Nanoscale Most Popular Articles 2018” List

         

        For our publication highlights and full list see:   http://www.bohndieklab.org/publications